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This site is dedicated to advancing drug abuse research around the globe by fostering international cooperative research and supporting the exchange of scientific information. Investigators can network and form workgroups in The Exchange, access international drug abuse survey data, clinical trials information and statistical training inThe Toolkit . Read more about the network.


Drug addiction dramatically shifts a person’s attention, priorities, and behaviors toward a focus almost entirely on seeking out and taking drugs. An animal study funded by NIDA has identified some of the specific long-term adaptations in the brain’s reward system that may contribute to this shift.
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For the first time, preliminary research using brain-imaging technology has shown that low-key and attention-grabbing anti-smoking public service announcements stimulate different patterns of activity in smokers' brains and that smokers are more likely to remember seeing the low-key PSAs.
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Repeated use of addictive drugs such as cocaine causes long-lasting changes in parts of the brain involved in motivation and reward, among others, yet the precise mechanisms by which these changes are maintained are poorly understood. A new study by scientists supported by the National Institute on Drug Abuse (NIDA), published May 14, 2009 in the journal Neuron, sheds light on this process by providing fundamental new insights into the effects of cocaine on the structure and function of the genome, the complete set of DNA instructions needed to make an organism.
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A resourceful study into the effect of third hand smoke upon the risk for genetic mutations in fruit flies won the top Addiction Science Award at this year's Intel International Science and Engineering Fair (ISEF), the world's largest science competition for high school students.
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The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, unveiled its first comprehensive Physicians' Outreach Initiative, NIDAMED, which gives medical professionals tools and resources to screen their patients for tobacco, alcohol, illicit, and nonmedical prescription drug use.
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